close someone up
to close a surgical wound at the end of a surgical procedure. Fred, would you close her up for me? Fred closed up the patient.
close something up
1. to close someone's business, office, shop, etc., temporarily or permanently. Tom's restaurant nearly went out of business when the health department closed him up. The health department closed up the restaurant.
2. to close something that is open, such as a door or a box. Please close the door when you leave.
close up
1. Lit. [for an opening] to close completely. The door closed up and would not open again. The wound will close up completely in a day or so.
2. Fig. [for a place of business] to close for business. The store closed up and did not open until the next day.