v.1. To administer drugs to someone or something: The coach doped the athletes up before the race, in violation of the rules. The nurse doped me up after my surgery.
2. To intoxicate someone with some drug: The kidnappers doped up their victim on sedatives. She doped herself up and went to a party. Does he always have to get doped up in order to enjoy himself?
3. To become intoxicated by taking some drug: The nervous passenger doped up on tranquilizers before the flight.