A thoughtful, well-reasoned guess; a guess with some basis in one's knowledge. Class, we've studied cells all semester. Take an educated guess as to what the answer might be.
a guess that is likely to be correct because you have enough knowledge about a particular subject Scientists can do no more than make educated guesses about future climate changes.
A speculation based on past experience or knowledge, as in I'm not sure how much meat we need to feed twelve, but I'll make an educated guess and say six pounds . [Mid-1900s]