v.1. To prevent something or someone from entering a space: The lid keeps the flies out of the jar. I have a screen door to keep out stray animals.
2. To remain in an external place: I respect your privacy; I'll keep out of your room. There are a dangerous animals in that cage, so keep out!
3. keep out of To refrain from interfering with something, especially someone's affairs: I think they should keep out of our argument. Keep the children out of it.
4. keep out of To prevent someone from interfering with something: I tried to keep the children out of our family's problems.