v.1. To disconnect from or stop receiving a particular broadcast station or program: I had to tune out halfway through the game last night, so I don't know how it ended.
2. Slang To disassociate oneself from one's environment: When faced with so much advertising, most people just tune out.
3. Slang To become unresponsive to someone or something; ignore someone or something: She tried to tune out the children's laughter so she could study. He tunes me out every time I ask him about the money that he owes me.