| Abbreviation | Definition |
|---|---|
| SOD | Summer Of Death |
| SOI | Structure Of the Intellect |
| SOMNIA | Spotlight On Military News and International Affairs |
| SPARS | Society of Professional Audio Recording Services |
| SPAWN | Small Press Artists and Writers Network |
| SPC | Student Paper Competition |
| SPEW | Society for Protection of Elvish Welfare |
| SPH | Singapore Press Holdings |
| SPN | Saint Petersburg News |
| SPN | Silicon Prairie News |
| SPSU | Satellite Processing System Upgrade |
| SPT | Small Press Traffic |
| SPTI | Sony Pictures Television International |
| SPU | Sound Pick Up (microphone) |
| SPU | Sub-Picture Unit |
| SRB | Software Research Bulletin |
| SRIS | Sunrise Ridge Intermediate School |
| SRN | Synchrotron Radiation News |
| SRNA | Srpska Republika News Agency |
| SSD | Single Sided Disk |