| Scotty | | - | English, Scottish | |
| Scout | | SKOWT | English (Rare) | |
| Sean | | SHAWN | Irish, English | |
| Seanna | | SHAW-nə | English (Rare) | |
| Sebastian | | ze-BAHS-tee-ahn (German), sə-BAS-chən (English), se-BAHS-tyahn (Polish), SE-bahs-tee-ahn (Finnish) | German, English, Swedish, Norwegian, Danish, Polish, Finnish, Romanian | |
| Sefton | | SEF-tən | English (Rare) | |
| Selby | | SEL-bee | English (Rare) | |
| Selina | | - | English | |
| Selma | | SEL-mə (English), ZEL-mah (German) | English, German, Dutch, Swedish, Norwegian, Danish, Icelandic | |
| Selwyn | | SEL-win | English (Rare) | |
| September | | sep-TEM-bər | English (Rare) | |
| Sequoia | | sə-KOI-ə | English (Rare) | |
| Sera | | SER-ə | English (Rare) | |
| Seraphina | | - | English (Rare), German (Rare), Late Roman | |
| Serena | | sə-REEN-ə (English), se-RE-nah (Italian) | English, Italian, Late Roman | |