| Emmanouil | | - | Greek | |
| Endymion | | - | Greek Mythology | |
| Enoch | | EE-nək (English) | Biblical, Biblical Latin, Biblical Greek | |
| Enos | | EE-nahs (English) | Biblical, Biblical Latin, Biblical Greek | |
| Enyo | | - | Greek Mythology | |
| Eos | | e-aws (Ancient Greek), EE-aws (English) | Greek Mythology | |
| Epaphras | | EP-ə-fras (English) | Biblical, Ancient Greek, Biblical Greek, Biblical Latin | |
| Epaphroditos | | ee-paf-rə-DIE-təs (English) | Ancient Greek | |
| Ephraim | | EE-free-im (English), EE-frəm (English), E-free-im (English), E-frəm (English) | Biblical, Jewish, Biblical Latin, Biblical Greek | |
| Ephrath | | - | Biblical, Biblical Latin, Biblical Greek | |
| Epiktetos | | - | Ancient Greek | |
| Epimetheus | | - | Greek Mythology | |
| Epiphanes | | - | Ancient Greek | |
| Epiphanios | | - | Ancient Greek | |
| Epiphanius | | - | Ancient Greek (Latinized) | |