| Name | Gender | Pronounced | Usage | Popularity |
|---|---|---|---|---|
| Sacagawea | - | Native American | ||
| Sacnite | - | Native American, Mayan | ||
| Saqui | - | Native American, Mapuche | ||
| Sayen | - | Native American, Mapuche | ||
| Shanice | shə-NEES | African American (Modern) | ||
| Shanika | shə-NEE-kə | African American (Modern) | ||
| Shaniqua | shə-NEE-kwə | African American (Modern) | ||
| Shelena | - | African American (Rare) | ||
| Shikoba | - | Native American, Choctaw | ||
| Sissinnguaq | - | Native American, Greenlandic |