have two strikes against (one)
To be at a deficit or disadvantage, nearing failure. The phrase comes from baseball, in which a batter is called "out" after three strikes. Man, I already have two strikes against me in that class, I can't turn in my project late too! You have two strikes against you from putting a dent in my car and getting a speeding ticket—if anything happens this week, your driving privileges will be taken away.