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3. in spite of

in spite of

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in spite of someone or something

without regard to someone or something; even though another course had been prescribed; ignoring a warning. In spite of her orders to stay, I left. In spite of the bad weather, I had fun on vacation.

See also: of, spite

in spite of something

even while recognizing something bad In spite of the problems they’ve faced, they are happy with the life they lead. The drug maker won't change the labeling on its product, in spite of six recent deaths tied to the drug.

Usage notes: used to say that the something bad will not strongly influence you

See also: of, spite

in spite of

Regardless of, in defiance of, as in They kept on in spite of their fears. [c. 1400]

See also: of, spite

in spite of

Not stopped by; regardless of: They kept going in spite of their fears.

See also: of, spite