v.1. To cause someone or something to fall by a blow: Boxing experts are predicting that the champion will strike down the contender in the third round. I grabbed a wrench and struck the intruder down with a blow to the head.
2. To incapacitate or kill someone. Used chiefly in the passive: Hundreds of civilians were struck down during the first week of the war. Smokers need to realize that heart disease can strike them down in the prime of their lives.
3. To render something ineffective; cancel something: The committee struck down the proposal we've worked so hard on, so we'll have to start all over again. The Supreme Court determined that the law was unconstitutional and struck it down accordingly.