Also,
what's bugging you. What is annoying or bothering you? For example,
We've conceded just about every point, so what's eating you now? or
You're in a terrible mood-what's bugging you? The first slangy term, dating from the late 1800s, presumably uses
eat in the sense of "consume"; the colloquial variant, from about 1940, uses
bug in the sense of "annoy." Also see
what's with.