v.1. To remove something from the surface of something or someone by wiping: Between the games, I wiped the sweat off my forehead and had a drink of water. I wiped the fog off my glasses.
2. To remove something, especially a liquid, by wiping: I tried to wipe off the water, but the seat was still damp. I scrubbed so hard that I wiped the paint off. I wiped off the sweat from my forehead.
3. To clean or dry the surface of something or someone by wiping: Wipe off your feet before you enter the house. I washed the dishes and wiped them off.
4. To eliminate something from or as if from some surface: A nuclear war could wipe us all off the earth. Wipe that smile off your face! The tornado wiped the village off the map.