v.1. To destroy something completely; obliterate something: A mudslide wiped out the road to the village. Another strong wind could wipe the damaged building out completely.
2. To kill someone or something, especially a group or part of a group: The invaders wiped out the entire population of the countryside. This disease could wipe many of the villagers out.
3. To exhaust the strength or energy of someone; wear someone out: The hike up the mountain wiped us out. The long practice wiped out the whole football team.
4. To reduce some value or amount to zero or nothing: The reckless spending wiped out the budget surplus. The company's renewed sales wiped their debts out completely.
5. To reduce someone to poverty or bankruptcy: A bad harvest wiped out the remaining farms. My travel expenses are going to wipe me out.
6. To invalidate or nullify something: A grand slam wiped out six innings of flawless pitching. A silly remark wiped the politician's reputation out completely.
7. To erase data from some computer storage device: The program wipes out the old data before writing the new data. Reformatting a disk will wipe it out.
8. To lose one's balance and fall, as when skiing or surfing: At the top of the hill, I wiped out and nearly hit another skier.