| Abbreviation | Definition |
|---|---|
| SPECT | Single photon emission tomography |
| SPEED | Self Programmed Electronic Equation Delineator |
| SPEG | Solid Phase Epitaxy Growth |
| SPER | South Pacific Electric Railway |
| SPG | Sync Pulse Generator |
| SPI | Serial Peripheral Interface |
| SPI | Solder Paste Inspection |
| SPI | Split Port Induction |
| SPICE | Simulation Program For Integrated Circuit Emulation |
| SPIDER-MEM | SEMATECH Process-Induced Damage Effect Revealer - Manufacturing Equipment Monitor |
| SPIN | Software Process Improvement Network |
| SPL | Speech Perception Level |
| SPLIC | Special-Purpose Linear Integrated Circuit |
| SPM | Scanning Probe Microscopy |
| SPM | Sound Powered Microphone |
| SPN | Sequential Phase Number |
| SPN | Shift Pulse Network |
| SPN | Signal Plus Noise |
| SPN | Signal Processor Network |
| SPN | Single Pole Network |