| Abbreviation | Definition |
|---|---|
| SOLTIP | SOLar connections to Transient Inter-planetary Processes |
| SONAR | SOund Navigation And Ranging |
| SOON | Solar Observing Optical Network |
| SOONSPOT | SOON's Solar Patrol on Tape |
| SOP | Ship-of-Opportunity Program |
| SOPAC | South Pacific Applied Geoscience Commission |
| SOPS | Select Committee on Ocean Policy |
| SOR | School of Rock |
| SORD | Special Operations and Research Division |
| SOS | Satellite Observing System |
| SOS | Southern Oxidant Study |
| SOSC | Smithsonian Oceanographic Sorting Center |
| SOST | Subcommittee on Ocean Science and Technology |
| SOWEX | Southern Ocean Waves Experiment |
| SPADE | Stratospheric Photochemistry, Aerosols, and Dynamics Expedition |
| SPAM | South Pole Area Manager |
| SPAN | Space Physics Analysis Network |
| SPARC | Stratospheric Processes and their Role in Climate |
| SPARS | Software Procurement And Renewal System |
| SPC | South Pacific Commission |