| Abbreviation | Definition |
|---|---|
| DOMSAT | DOMestic SATellite |
| DON | Dissolved Organic Nitrogen |
| DOO | Departmental Organization Order |
| DOPLIGHT | DOPpler-LIGHTing |
| DOPLOON | Doppler Balloon |
| DORIS | Doppler Orbitography and Radiopositioning Integrated by Satellite |
| DOS | Department Of State |
| DOT | Department Of Transportation |
| DOTREX | Deep Ocean Tracer Experiment |
| DPC | Domestic Policy Council |
| DPP | Disaster Prevention and Preparedness |
| DRASER | Doppler Radar And Storm Electricity Research |
| DRS | Data Receiving System |
| DSC | Digital Switching Company |
| DSDP | Deep Sea Drilling Project |
| DSL | Deep Scattering Layer |
| DSOG | Deep Submergence Operations Group |
| DSS | Dive Safety System |
| DSSP | Deep Submergence Systems Project |
| DSV | Deep Sea Vessel |