| Abbreviation | Definition |
|---|---|
| ISCA | International Student Christian Association |
| ISCA | Iowa Student Computer Association |
| ISCA | Iranian Student Cultural Association |
| ISCO | Indian Students Cultural Organisation |
| ISCO | Iranian Student Cultural Organization |
| ISD | Instructional Support Department |
| ISD | Instructional Systems Design |
| ISDA | Irish Student Drama Awards |
| ISDL | Instrument Systems Development Laboratory |
| ISDL | Integrated Systems Design Laboratory |
| ISDP | Independent Study Degree Program |
| ISDP | Institutional Support and Development Program |
| ISDR | Institut Superieur de Developpement Rural |
| ISDS | Institute of Statistics and Decision Sciences |
| ISDS | IRAC Science Data Simulator |
| ISE | Information and Systems Engineering |
| ISE | Institutional Student Employee |
| ISE | Instructional Support and Enhancement |
| ISE | International Student Exchange |
| ISE | International Students Enschede, the Netherlands |