| Abbreviation | Definition |
|---|---|
| USC | University of San Carlos |
| USC | University of South Carolina |
| USC | University of South Cuba |
| USC | University of Southern California |
| USC | University of Stylish Canines |
| USC | University Senior College |
| USC | University Souhern California |
| USC | University Students Council |
| USCA | University of South Carolina Aiken |
| USCA | University of Spa and Cosmetology Arts |
| USCA | University Students' Cooperative Association |
| USCB | Universitats-Segel-Club Bochum |
| USCB | University of South Carolina - Beaufort |
| USCB | University of South Carolina Beaufort |
| USCB | University of South Carolina Beaufort's |
| USCC | United Students of Color Council |
| USCGA | United States Coast Guard Academy |
| USCGAPA | United States Coast Guard Academy Parents' Association |
| USCGH | University of South Carolina Grade Hours |
| USCGK | University of South Carolina Golden Key International Honour Society |