| Abbreviation | Definition |
|---|---|
| ISC | Information Security Company |
| ISC | Interconnect Solutions Company |
| ISC | International Skychase Corporation |
| ISC | International Sound Corporation |
| ISC | International Speedway Corporation |
| ISC | Invention Submission Corporation |
| ISCC | Independent Schools Compensation Corporation |
| ISCI | Industrial Safety Consultants Incorporated |
| ISCL | International Securities Company Limited |
| ISCNZ | Immigration Services Centre New Zealand |
| ISD | Information Services Division |
| ISD | Integrated Solutions Division |
| ISDA | International Swaps Dealers Association |
| ISDI | International Seminar Design Inc |
| ISDM | International Swiss Debt Management |
| ISDS | International Security Defense Systems |
| ISES | International Student Exchange Services |
| ISF | International Selection Fund |
| ISFC | India Shelter Finance Corporation |
| ISFC | Indian School Finance Company |