| Abbreviation | Definition |
|---|---|
| OSP | Old School Productions |
| OSP | Open Studios Press |
| OSP | Orange Smoothie Productions |
| OSR | Open Systems Resources, Inc. |
| OSRAM | OSmium and wolfRAM |
| OSRC | Ondo State Radiovision Corporation |
| OSRC | Open Source Robotics Corporation |
| OSRTC | Odisha State Road Transport Corporation |
| OSRTC | Orissa State Road Transport Corporation |
| OSS | Open Source Software |
| OSS | Open Source Solutions |
| OSS | Oracle Support Services |
| OSS | Organex Software Services |
| OSS | Orthopaedic Spine Specialists |
| OSS | Orthopaedic & Spine Specialists |
| OSSS | One Stop Satellite Solutions |
| OSSS | One-Stop Shop Service |
| OSTC | One Stop Travel Company |
| OSTC | Owen Sound Transportation Company |
| OSW | Oley Sled Works |