| Abbreviation | Definition |
|---|---|
| ISIA | Improving America's Schools Act |
| ISIS | Independent Schools Information Service |
| ISIS | Information Services In Schools |
| ISIS | Initiative for Schools, Industries, and Sciences |
| ISIS | International Studies for Indiana Schools |
| ISIS | Internet Student Information System |
| ISIS | Iowa Student Information Services |
| ISL | International Service Learning |
| ISL | Introduction to Statistical Learning |
| ISL | Inuit Sign Language |
| ISLC | Imagination Station Learning Center |
| ISLC | International Studies Learning Center |
| ISLE | Illinois Shared Learning Environment |
| ISLE | Informal Sustainability Learning Environment |
| ISLE | Interactive Spoken Language Education |
| ISLE | Intercollegiate Sri Lanka Education |
| ISLG | Intelligent Support for Learning in Groups |
| ISLP | Interprofessional Service Learning Project |
| ISLT | Instructional Systems and Learning Technologies |
| ISLT | Instructional Systems Learning Technologies |