| Abbreviation | Definition |
|---|---|
| SPAN | Serials Periodicals And Newspapers |
| SPARS | The Society Of Professional Audio Recording Services |
| SPAZ | Special Agent Zero |
| SPD | Small Press Distribution |
| SPECTRE | SPecial Executive for Counterintelligence, Terrorism, Revenge, and Extortion |
| SPHE | Sony Pictures Home Entertainment |
| SPIN | Strategic Press Information Network |
| SPIN | Strategic Progressive Information Network |
| SPLM | Shielded Planar Layered Media |
| SPOD | Slant Path Optical Depth |
| SPQ | Smithsonian Preservation Quarterly |
| SPQ | Social Psychology Quarterly |
| SPQ | Stories, Poems, and Quotes |
| SPR | Saving Private Ryan (movie) |
| SPUR | Speed Photography Ultrahigh Resolution |
| SPV | Sound Picture And Video |
| SPV | Sound, Pictures, and Video |
| SPV | SPelling Variant |
| SPW | The Sports Wire |
| SQ | Single Quotes |