| Abbreviation | Definition |
|---|---|
| SAL | SORITEC Datafile |
| SAM | Samna - Lotus Ami/ Ami Pro Text file |
| SAR | SAR Compressed file archive |
| SAS | SAS source code file |
| SAV | Saved backup or configuration data |
| SAV | SAVed Game Situation |
| SAV | Service Application Visoft |
| SB | Signed Byte Audio file |
| SBD | Storyboard Editor Data file |
| SBI | Sound Blaster Instrument |
| SBK | Asymetrix Toolbook files |
| SBK | Emu SoundFont Bank |
| SBL | Stony Brook Pascal Library |
| SBP | Superbase 4 DML program |
| SBR | Source Browser Support file |
| SBT | Superbase 4 for Windows, Notes related to record |
| SBXLS | Sandboxels saved game |
| SC | Framework II Display driver |
| SC | Paradox PAL script file |
| SC2 | Microsoft Schedule+ 7.x Document file |