| Abbreviation | Definition |
|---|---|
| DPX | Bitmap graphics (Digital Moving Picture Exchange) (Cineon DPX file) |
| DRA | Nuance Dragon Voice Recording File |
| DRS | Display Resource (WordPerfect for Win) |
| DRV | Device driver (for hardware) |
| DRW | Micrografx Designer Vector graphics format file |
| DS4 | Micrografx Designer 4.x Vector graphics file |
| DSC | Description file |
| DSC | Discard file (Oracle) |
| DSC | Oracle Discard file |
| DSC | Oracle Discard file |
| DSD | DataShaper Database file |
| DSF | Delusion Digital Sound File (Delusion) |
| DSK | Borland C++ Project desktop file |
| DSK | Novell NetWare Disk Drivers |
| DSM | Digital Sound Module |
| DSM | Microsoft Developer Studio Macro |
| DSN | Object System Designer Design file |
| DSN | ODBC data source |
| DSP | Display parameters (Signature) |
| DSP | Dr.Halo Graphics DISplay driver |