| Abbreviation | Definition |
|---|---|
| CLR | Common Language Runtime |
| CLS | Common Language Specification |
| CLT | Color Lookup Table |
| CLUE | Canadian Linux Users Exchange |
| CLUE | Colorado Linux Users and Enthusiasts |
| CLUT | Color Look Up Table |
| CLW | Character Line And Word |
| CM | Computer Modeled |
| CM | Contextual Menus |
| CM/2 | Communication Manager / 2 |
| CMC | Communication Management Configuration |
| CMEA | Council for Mutual Economic Assistance |
| CMF | Common Maintenance Framework |
| CMF | Computer Maintenance Facility |
| CMF | Content Management Framework |
| CMGC | Construction Manager General Contractor |
| CMIP | Common Management Information Protocol |
| CMIS | Common Management Information Service |
| CMK | Cyan, Magenta, Black |
| CML | Configuration Management Log |