| Abbreviation | Definition |
|---|---|
| ERS | External Reference Specification |
| ERTEE | Everything is Related to Everything Else |
| ERU | Emergency Recovery Utility |
| ES | Errored Second |
| ES | Event Sequence |
| ESA | Extended Service Area |
| ESC | Entire System Crashes |
| ESCON | Enterprise System Connection Architecture |
| ESD | Electronic Software Distribution |
| ESD | electrostatic discharge |
| ESD | Enhanced Swap Disc |
| ESD | External Symbol Dictionary |
| ESDI | Enhanced Small Device Interface |
| ESDI | Enhanced Small Drive Interface |
| ESDS | Entry Sequenced Data Set |
| ESF | Extended SuperFrame |
| ESM | Enterprise Systems Management |
| ESP | Extra Sprite Palette |
| ESPRIT | European Strategic Programme for Research and development in Information Technology |
| ESQA | Extended System Queue Area |