| Abbreviation | Definition |
|---|---|
| SPE | Service Processing Element |
| SPED | Shortest Path Evaluation Device |
| SPI | SCSI-3 Parallel Interface |
| SPI | Security Parameter Index |
| SPI | Session Parameter Index |
| SPI | Stateful Packet Inspection |
| SPI | Statefull Packet Inspection |
| SPI | Subsequent Protocol Identifier |
| SPID | Secure Protocol Implementation Development |
| SPINDLE | Synergy Professionalism Innovation Networking Development Leadership and Empowerment |
| SPLC | Smart Predictive Line Controller |
| SPM | Session Protocol Machine |
| SPM | Software Performance Monitor |
| SPM | Standard Port Monitor |
| SPM | System Performance Monitor |
| SPN | Secure Private Network |
| SPN | Service Principal Names |
| SPP | Serial Port Profile |
| SPP | Session Participation Probability |
| SPP | Standard Parallel Port |