| Abbreviation | Definition |
|---|---|
| OPB(ORA) | Operations and Policy Branch (Office of Regulatory Affairs) |
| OPD | Office of Orphan Products Development |
| OPD(OC) | Office of Orphan Products Development (OC) |
| OPDFB | Office of Plants, Dairy Foods, and Beverages |
| OPDP | Office of Prescription Drug Promotion (CDER) (formerly Division of Drug Marketing, Advertisement and |
| OPF | Official Personnel Folder |
| OPFIT | Office of Planning, Finance, and Information Technology |
| OPFIT(NCTR) | Office of Planning, Finance and Information Technology (NCTR) |
| OPHEP | Office of Public Health Emergency Preparedness |
| OPI | Office of Performance Improvement |
| OPI | Office of Planning and Informatics |
| OPL | Office of PLanning |
| OPL(OC) | Office of Planning (OC) |
| OPM | Office of Personnel Management |
| OPMAD | Orthopedic Physical Medicine and Anesthesiology Devices Branch |
| OPMAD(CDRH) | Orthopedic Physical Medicine and Anesthesiology Devices Branch (CDRH) |
| OPO | Organ Procurement Organization |
| OPPB | Office of Policy, Planning and Budget |
| OPPL | Office of Policy, Planning, and Legislation |
| OPPL(OC) | Office of Policy, Planning and Legislation (OC) |