| Abbreviation | Definition |
|---|---|
| FR | Firing Room |
| FR | Flight Rule |
| FR | FRame |
| FRAGNET | FRAGmented NETwork |
| FRAM | Flight Release Attach Mechanism |
| FRB | Fuel Reduction Burn |
| FRC | Flight Research Center |
| FRCI | Fibrous Refractory Composite Insulation |
| FRCS | Forward Reaction Control System |
| FRD | Flight Requirements Document |
| FRE | Flight Related Element |
| FRE | Format Request Element |
| FRED | First Robotic Exploring Device |
| FREQ | FREQuency |
| FREQCONV | FREQuency CONVerter |
| FREQDIV | FREQuency DIVider |
| FRF | Flight Readiness Firing |
| FRFT | Flight Readiness Firing Test |
| FRJD | Forward Reaction Jet Driver |
| FRL | Frame Reference Line |