| Abbreviation | Definition |
|---|---|
| FSL | Fluid Science Laboratory |
| FSLO | First Spacelab PayLOad |
| FSLT | First Sea Level Test |
| FSM | Flight Synchronizer Module |
| FSM | Fuel Supply Module |
| FSMF | Flight Software Maintenance Facility |
| FSO | Functional Supplementary Objective |
| FSOH | Flight Support Operations Handbook |
| FSOP | Florida Safety Operating Plan |
| FSP | Fault Summary Page |
| FSPAAD | Fine Sun Pointing Attitude Anomaly Detection |
| FSR | Final System Release |
| FSR | Flight-Specific Requirement |
| FSRR | Facility System Requirements Review |
| FSRR | Flight Software Readiness Review |
| FSRS | Flight System Recording System |
| FSS | Field Spectrometer System |
| FSS | Fire Suppression System |
| FSS | Fixed Service Structure |
| FSS | Flight Support Station |