| Abbreviation | Definition |
|---|---|
| ILS | Integrated Logistics System |
| ILS/LAR | Integrated Logistics System and Logistics Assess Review |
| ILSSE | Integrated Life Science Shuttle Experiments |
| IM | Information Memory |
| IM | Instrument Module |
| IM | Interface Module |
| IM | Interim Mission |
| IM | Intermediate Moisture |
| IM | Inverse Maneuver |
| IMAGE | Imager for Magnetopause to Aurora Global Exploration |
| IMAP | Integrated Mission Analysis Planning |
| IMAX | High-definition Shuttle Cabin Camera |
| IMAX | Shuttle Cabin Camera (Manufactured by IMAX, Inc.) |
| IMBLMS | Integrated Medical and Behavioral Laboratory Measurement System |
| IMC | Image Motion Compensation |
| IMCC | Integrated Mission Control Center |
| IMCP | Integrated Monitor and Control Panel |
| IMD | InterMeDiate |
| IMDB | Integrated Maintenance Data Base |
| IME | International Magnetospheric Explorer |