| Abbreviation | Definition |
|---|---|
| ODAS | Onboard Data Acquisition System |
| ODB | Operational Data Book |
| ODCDR | Orbiter Delta CDR |
| ODDS | Operational Data Delivery Services |
| ODES | Optical Discrimination Evaluation Study |
| ODF | Orbit Determination Facility |
| ODIN | Orbital Design Integration (System) |
| ODIN | Outsourcing Desktop Initiative for NASA |
| ODIN | Outsourcing Desktop Initiative for NASA/KSC |
| ODIN | Outsourcing Desktop Initiative for NASA/KSC (Kennedy Space Center) |
| ODP | Operational Display Procedure |
| ODR | Output Data Redundancy |
| ODRAN | Operational Drawing Revision Advance Notice |
| ODS | Orbiter Docking System |
| ODSN | Optical Deep Space Network (US NASA) |
| ODU | Output Display Unit |
| OE | Operator Error |
| OEAS | Orbital Emergency Arresting System |
| OECO | Outboard Engine Cutoff |
| OECO | Outboard Engine Cut-Off |