| Abbreviation | Definition |
|---|---|
| OLF | Orbiter Landing Facility (now SLF) |
| OLF | Orbiter Lifting Frame |
| OLIA | Office of Legislative Intergovernmental Affairs |
| OLIA | Office of Legislative & Intergovernmental Affairs |
| OLIF | Orbiter Landing Instrumentation Facilities |
| OLOW | Orbiter Lift-Off Weight |
| OLSA | Orbiter/LPS Signal Adapter |
| OLSP | Orbiter Logistics Support Plan |
| OM | Onboard Mop |
| OM | Operational Mid-MDM (Manipulator Deployment Mechanism) |
| OM | Optical Master |
| OM | Overall Maintenance |
| OM&M | Operations, Maintenance, and Monitoring |
| OMA | Operations Maintenance Area |
| OMA | Operations Management Application |
| OMA | Orbiter Maintenance Area |
| OMBUU | Orbiter Midbody Umbilical Unit |
| OMC | Operations Management Center |
| OMC | Orbiter Maintenance and Checkout |
| OMCF | Operations and Maintenance Control File |