| Abbreviation | Definition |
|---|---|
| SA | Supplemental Agreement |
| SA | Support Area |
| SA | Supportability Analysis |
| SAA | South Atlantic Anomaly |
| SAA | System Assurance Analysis |
| SAAB | Space Above And Beyond |
| SAAC | Schedule Allocation and Control |
| SAALC | San Antonio Air Logistics Center |
| SAAM | Special Air Force Airlift Mission |
| SAAMA | San Antonio Air Material Area |
| SAAS | Shuttle Aerosurface Actuator Simulation |
| SAB | Shuttle Avionics Breadboard |
| SAB | Spacecraft Assembly Building |
| SAB | Storage and Assembly Building |
| SAC | Shuttle Action Center |
| SAC | Shuttle Action Center (HOSC) |
| SAC | Strategic Air Command (USAF) |
| SAC | Support Action Center |
| SACS | Software Avionics Command Support |
| SACS | Systems Software Avionics Command Support |