| Abbreviation | Definition |
|---|---|
| SDV | Shuttle Derived Vehicle |
| SDVF | Software Development and Verification Facilities |
| SE | Science and Engineering |
| SE | Student Experiment |
| SE | System Element |
| SE | Systems Engineering |
| SE/FAC | Support Equipment/Facility |
| SEA | Scanning Electrostatic Analysis |
| SEA | Sensor Electronics Assembly |
| SEA | Silicon Elastimeter Ablator |
| SEACF | Support Equipment Assembly and Checkout Facility |
| SEADS | Shuttle Entry Air Data Sensor |
| SEADS | Shuttle Entry Air Data System |
| SEADS | Shuttle Entry Air Data System (Subsystem) |
| SEAID | Support Equipment Abbreviated Items Description |
| SEAPG | Support Equipment Acquisition Planning Group |
| SEARCHS | Shuttle Engineering Approach/Rollout Control Hybrid Simulation |
| SEB | Scientific Equipment Bay |
| SEB | Source Evaluation Board |
| SEB | Support Equipment Building |