| Abbreviation | Definition |
|---|---|
| STD | Shuttle Test Director |
| STD | Standard Transmission Difficulties |
| STDCE | Surface Tension Driven Convection Experiment |
| STDCF | Space Telescope Data Capture Facility |
| STDL | Standard Distribution List (letter denoting which list follows) |
| STDM | Space Technology for Disaster Management |
| STDN | Spaceflight Tracking and Data Network |
| STDY | Steady |
| STE | System Test Engineer |
| ST-ECF | Space Telescope European Coordinating Facility |
| STEP | Space Technology Experiments Platform |
| STEREO | Solar Terrestrial Relations Observatories |
| STEX | Sensor Technology Experiment |
| STF | Software Test Facility |
| STF | Spin Test Facility (see DSTF) |
| STF | Structural Fatigue Test |
| STG | Stage |
| STGT | Second TDRSS Ground Terminal |
| STHP | Space Telescope History Project |
| STI | Satellite Transmitted Image |