| Abbreviation | Definition |
|---|---|
| CHS | Collimated Hole Structure |
| CHUTE | ParaCHUTE |
| CHX | Cabin Heat eXchanger |
| CI | Certification Inspection |
| CI | Color Interior film |
| CI | Configuration Inspection |
| CI | Continuous Interlock |
| CI | Course Invalid |
| CI | Crew Interface |
| CIA | Control Interface Assembly |
| CIAP | Climatic Impact Assessment Program |
| CIAR | Change Implementation/Assessment Record |
| CIB | Change Impact Board |
| CIB | Change Implementation Board |
| CIB | Cosmic Infrared Background |
| CIC | Command Interface Control |
| CIC | Communications Interface Coordinator |
| CIC | Continuing Improvement Council |
| CIC | Control and Information Center |
| CIC | Crew Interface Coordinator |