| Abbreviation | Definition |
|---|---|
| SCAM | Scheming Criminals After Money |
| SCAN | Scanning |
| SCD | Something Completely Different |
| SCDG | S*** City Dream Girls |
| SCG | Senior College Girl |
| SCI | Sophisticated Creative And Intelligent |
| SCION | Super Cramped Inside Ouch Neckpain |
| SCMB | Somebody Catch My Breath |
| SCNR | Sorry, Could Not Resist |
| SCOTSB | Steph Curry On The Shot Bruh |
| SCP | Slow Computer Problems |
| SCRAP | Sidewinding Crazy Radical A** Punches |
| SCREAM | Situation, Circumstance, Respect, Education, Attitude, Make |
| SCREAM | Situation, Circumstance, Respect, Education, Attitude, Make |
| SCS | Soc Culture Scottish |
| SCS | Soc Culture Soviet |
| SCUD | Suddenly Comes Un-Desireable |
| SCUM | Sharing Caring Urban Male |
| SD | Saved the Day |
| SD | Stranger Danger |