| Abbreviation | Definition |
|---|---|
| SOSDD | Same Old Shit, Different Day |
| SOTR | Stand Outside The Real |
| SOTS | Snow On The Steps |
| SOURCE | Sovereign Omnilord Of Unanimous Regency And Caliber Excaliper |
| SOY | Straight Outta York |
| SP | South Park |
| SP | Super Pud |
| SPA | Self Propelled Adrenaline |
| SPA | Sonic Pocket Adventure |
| SPA | Spam Protection Agency |
| SPACE | Sisters Playful Anarchy Causes Emergency |
| SPAD | Simple Plastic Aeroplane Design |
| SPAM | Self Promotional Advertising Messages |
| SPAM | Sending People Annoying Mail |
| SPAM | Sending Persistently Annoying Mail |
| SPAM | Senseless Pointless Annoying Message |
| SPAM | Sentient Paranormal Ameboid Mass |
| SPAM | Septic Products As Munchies |
| SPAM | Severely Punctured Artery Material |
| SPAM | Sewer Products Are Mmmmgood |