| Abbreviation | Definition |
|---|---|
| USC | United States of Consciousness |
| USC | University of Second Choice |
| USC | University of Service and Compassion |
| USC | University of Snobbish Children |
| USC | University of Spoiled Children |
| USC | University of Steroids and Creatine |
| USC | University of Stupid Children |
| USD | Uncle Sugar Daddy |
| USD | University of Spoiled Daughters |
| USDA | United States Despatch Agency |
| USDA | Useless Students Demanding Attention |
| USDF | United States Dung Federation |
| USEM | United States Egg Marketers |
| USIA | UnSanitary and Ignorant Aliens |
| USIGS | Universal Subtle Informational Gesture System |
| USL | University of Slow Learners |
| USMC | U Signed the Muthafrigging Contract |
| USMC | U'll See Much Cum |
| USMC | Uncle Sam's Misguided Children |
| USMC | Uncle Sam's Murder Club |