| Abbreviation | Definition |
|---|---|
| SOTI | Society Of The Insanes |
| SOTTET | Star Ocean: Till The End of Time |
| SOV | Sisters Of Vengeance |
| SOZ | Son Of Zeus |
| SPASM | Space Pirate Assault Station Meteoroid |
| SPC | Space People Carrier |
| SPC | Space Pioneer Confederation |
| SPC | Star Patrol Cruiser |
| SPD | Solar Patrol Delta |
| SPD | Space Patrol Delta |
| SPEW | Self Protecting Explosive Wand |
| SPEW | Speciated Particulate Emissions Wizard |
| SPIN | Senate Planetary Intelligence Network |
| SPO | Space Pirate Organization |
| SPOCK | Star Pilot On Channel K |
| SPOCK | Star Pilots On Channel K |
| SPQR | Sonthonax Power Quest for Rome |
| SPRIG | Staffordshire Paranormal Research and Investigation Group |
| SPUR | Society for Paranormal and UFO Research |
| SQC | StarQuest Club |