| Abbreviation | Definition |
|---|---|
| SOSF | Save Our Seas Foundation |
| SOT | Save Our Tamagotchies |
| SOWF | Special Operations Warrior Foundation |
| SP | Samaritan's Purse |
| SPA | Societa Per Azione |
| SPA | Société Protectrice des Animaux |
| SPAN | Single Payer Action Network |
| SPAN | Social Policy Action Network |
| SPAN | Solidarity Philippines Australia Network |
| SPAN | Spay/Neuter Animal Network |
| SPAN | Special Needs Advocacy Network |
| SPAN | Statewide Parent Advocacy Network |
| SPAN | Suicide Prevention Action Network |
| SPAR | Serving People and Animals Right |
| SPARC | Society for Promotion of Area Resource Centres |
| SPARK | Single Parents Alliance for Raising Kids |
| SPAT | Single Parents Alone Together |
| SPBC | Southern Piedmont Beacon Community |
| SPC | Societies and Publications Committee |
| SPC | Strategic Planning Conference |