| Abbreviation | Definition |
|---|---|
| S3&K | Sonic 3 Knuckles (Sonic 3 and Sonic Knuckles combination) |
| S3&K | Sonic 3 & Knuckles (Sonic 3 and Sonic & Knuckles combination) |
| SA | Super Armor |
| SAAT | San Andreas Audio Toolkit |
| SAB | Super Armor Break |
| SAGEN | Social Anime Gaming Entertainment Network |
| SALI | SIMS Access LAN Interface |
| SAMP | San Andreas Multiplayer |
| SAP | Slight Atari Player |
| SAQ | Speed, Agility, Quickness |
| SARE | Spam Assassin Rules Emporium |
| SARPBC | Supersonic Acrobatic Rocket-Powered Battle-Cars |
| SAT | Survive and Thrive |
| SBBM | Super Bounce Ball Maze |
| SBG | Server Based Gaming |
| SBG | Soulless Brigade Gaming |
| SBG | Stay Bizzy Gaming |
| SBGS | Server Based Gaming Systems |
| SBLJ | Side Backwards Long Jump |
| SBTW | Streamer By The Way |