| Abbreviation | Definition |
|---|---|
| IS | Intermediate System |
| IS | International Standard |
| ISA | Informix Server Administrator |
| ISAM | Indexed Sequential Access Method |
| ISC | Implementation Specific Class |
| ISC | Interactive System Control |
| ISCII | Indian Standard Code for Information Interchange |
| ISCRA | Italian SuperComputing Resource Allocation |
| ISDN | Integrated System Development Network |
| ISDP | In-Situ Data Products |
| ISEB | Information Systems Examination Board |
| ISEM | Information Systems Engineering Methodology |
| ISFMS | Indexed Sequential File Management System |
| ISGP | Industrial Stormwater General Permit |
| ISIS | Image Structure Information And Style |
| ISIS | Import Support and Information System |
| ISIS | Information Services Integration Strategy |
| ISIS | Integrated Scientific Information System |
| ISIS | Integrated Spatial Information System |
| ISL | Initial System Load |