| Abbreviation | Definition |
|---|---|
| SPD | Single Programming Document |
| SPDIF | Sony Philips Digital Interface Format |
| SPDIF | Sony Phillips Digital Interchange Format |
| SPDU | Session Protocol Data Unit |
| SPE | Special Purpose Entity |
| SPECS | SDL Performance Evaluation of Concurrent Systems |
| SPEED | Small Profile Embedded Engine For Devices |
| SPG | Standard Procedure Guide |
| SPGP | State Programmatic General Permit |
| SPI | Serial Peripheral Interconnect |
| SPI | Single Process Initiative |
| SPI | Standard Performance Indicator |
| SPIFF | Still Picture Interchange File Format |
| SPK | Speaker |
| SPL | Sybyl Programming Language |
| SPL | Systems Programming Language |
| SPLA | Services Provider License Agreement |
| SPM | System Performance Monitor/2 |
| SPMN | Software Program Managers Network |
| SPN | Separation Program Number |