| Abbreviation | Definition |
|---|---|
| SIS | Streamlined Inspection System |
| SISCF/SIFCF | Survey of Inmates of State and Federal Correctional Facilities |
| SISTIR | Strategic Information Systems Technical Integration Resources |
| SITP | Strategic Information Technology Program |
| SITP(OC) | Strategic IT Programs (OC) |
| SL | Signature Line |
| SLIP | Serial Line Internet Protocol |
| SLIP | serial line internet protocol/point-to-point protocol |
| SLK | Statens Legemiddel Kontroll (Norwegian Medicines Control Authorities) |
| SLO | state liaison officer |
| SLR | Supplement Labeling Revision |
| SM | starting material |
| SMART | Submission Management and Review Tracking |
| SMB(OC) | Space Management Branch (OC) |
| SMCC | Standards Management Coordinating Committee |
| SMDA | Safe Medical Devices Act of 1990 |
| SME | Significant Medical Event |
| SMF | site master file |
| SMG | Staff Manual Guide |
| SMO | Site Management Organization |