| Abbreviation | Definition |
|---|---|
| APF | All-Pass Filter |
| APFR | Articulating Portable Foot Restraint |
| APG | Apogee |
| APID | Application Identification |
| APID | Applications Process IDentification |
| APM | Advanced Pressurized Module |
| APM | Antenna Pointing Mechanism |
| APM | Attached Pressurized Module |
| APME | Attitude Pointing Mechanism Electronics |
| APOD | Assistant Payload Operations Director |
| APOD | Astronomy Picture Of the Day |
| APPCM | Arm Pitch Plane Change Mode |
| APS | Acceleration and Pre-Separation |
| APS | Acquisition Processor Subsystem |
| APS | Advanced Positioning Sensor |
| APS | Alternate Payload Specialist |
| APS | Automated Payload Switch |
| APS | Auxiliary Power Supply |
| APT | Advanced Pointer Telemetry |
| APTU | Aerodynamic and Propulsion Test Unit |