| Abbreviation | Definition |
|---|---|
| SL-J | Japanese Spacelab |
| SLL | Shelf Life Limit |
| SLM | Simulated Laboratory Module |
| SLM | Sound Level Meter |
| SLMP | Space Launch Modernization Plan |
| SLN | ERNO Spacelab Payload |
| SLO | ERNO Spacelab Operations |
| SLOS | Star Line of Sight |
| SLP | ERNO Spacelab Program Office |
| SLP | Solar Lunar Planetary |
| SLPB | Spacelab Program Board |
| SLRV | Shuttle Launched Research Vehicle |
| SLS | Secondary Landing Site |
| SLS | Sortie Lab Simulator |
| SLS | Space Launch System |
| SLS | Spacelab Life Sciences |
| SLS | SpaceLab Simulator |
| SLS | Statement Level Simulator |
| SLSA | Shuttle Logistics Support Aircraft |
| SLSMS | Spacelab Support Module Simulator |